Fungicidal Impact of Salvadora Persica L. (Miswak) Extract on Growth of Foodborne Pathogens, Aspergillus Species.

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Fungicidal Impact of Salvadora Persica L. (Miswak) Extract on Growth of Foodborne Pathogens, Aspergillus Species.

Dose Response. 2019 Jul-Sep;17(3):1559325819876218

Authors: Saddiq AA, Alkinani MH

Abstract
Several investigations have focused on studying the suppressing influence of Salvadora persica (miswak) on oral microbes; however, studies regarding its fungicidal activity versus human aspergillosis-related illness are still scarce. The current research was designed to evaluate the fungicidal action of S persica aquatic root extract in terms of radial growth rate and inhibition zone (IZO) versus 3 pathogenic Aspergillus species, namely, A niger, A flavus, and A fumigatus in vitro. The results revealed that the plant extract (50 and 100 mg/mL) exhibited a prohibiting influence on the growth of the tested fungal species. The high concentration (100 mg/mL) of the plant extract was efficient in prohibiting the growing rate of the tested Aspergillus species after 6 days exposure period. Aspergillus niger and A flavus showed the largest inhibition ratios (60% and 54.4%, respectively) and IZO (33.00 ± 0.05 mm and 25.50 ± 0.18 mm, respectively) versus the control counterparts. Aspergillus fumigatus showed the minimum inhibition ratio (39%) and IZO (20.31 ± 0.05). The present data showed that the extract of S persica possesses potential fungicidal influence versus the tested pathogenic Aspergillus species and this may support the utilization of this extract as a promising antifungal agent versus aspergillosis.

PMID: 31598116 [PubMed]

Source: Industry