Isolation and Characterization of Two New Antimicrobial Acids from Quercus incana (Bluejack Oak).

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Isolation and Characterization of Two New Antimicrobial Acids from Quercus incana (Bluejack Oak).

Biomed Res Int. 2018;2018:3798105

Authors: Sarwar R, Farooq U, Naz S, Riaz N, Majid Bukhari S, Rauf A, Mabkhot YN, Al-Showiman SS

Abstract
Two new compounds [1-2] were purified from ethyl acetate fraction of Quercus incana. The structure of these compounds is mainly established by using advanced spectroscopic technique such as UV, IR, one-dimensional (ID) and two-dimensional (2D) NMR techniques, and EI mass. The structural formula was deduced to be 4-hydroxydecanoic acid [1] and 4-hydroxy-3-(hydroxymethyl) pentanoic acid [2]. Both isolated compounds were tested for their antimicrobial potential and showed promising antifungal activity against Aspergillus niger and Aspergillus flavus.

PMID: 29789786 [PubMed – in process]

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