MAIT Cell Activation by Fungal Pathogens.
Methods Mol Biol. 2020;2098:167-177
Authors: Jahreis S, Boettcher S, von Lilienfeld-Toal M
MAIT cells can recognize and respond to several pathogens in a distinct manner. However, many studies are focused on activation by bacteria and by viruses, while reports about molds and MAIT cells are rare. Here, we describe a method to investigate MAIT cell interaction with filamentous fungi from Aspergillus and Mucorales species. This includes preparation of fungal conidia, cell isolation, and analysis by flow cytometry.
PMID: 31792822 [PubMed – in process]