A pair of new tirucallane triterpenoid epimers from the stems of Picrasma quassioides.
Chin J Nat Med. 2019 Dec;17(12):906-911
Authors: Zhang J, Wang CX, Song XJ, Li S, Zhao H, Chen GD, Hu D, Gao H, Yao XS
A pair of new tirucallane triterpenoid epimers, picraquassins M and N (1> and 2), were isolated from the stems of Picrasma quassioides (D. Don) Benn. Their structures were determined based on comprehensive spectroscopic and X-ray crystallographic analyses. In addition, their AChE inhibitory activity, cytotoxicity against five human tumour cell lines (SW480, MCF-7, HepG2, Hela, and PANC-1), and antimicrobial activity against two bacteria (Staphylococcus. aureus 209P and Escherichia coli ATCC0111) and two fungi (Candida albicans FIM709 and Aspergillus niger R330) were evaluated.
PMID: 31882044 [PubMed – in process]