Alternative treatment of fungal infections: synergy with non-antifungal agents.
Mycoses. 2020 Oct 23;:
Authors: Rossato L, Dos Santos MC, Vitale RG, de Hoog S, Ishida K
Fungal infections are responsible for high mortality rates in immunocompromised and high-risk surgical patients. Therapy failures during the last decades due to increasing multidrug resistance demand innovative strategies for novel and effective antifungal drugs. Synergistic combinations of antifungals with non-antifungal agents highlight a pragmatic strategy to reduce the development of drug resistance and potentially repurpose known compounds with other functions to bypass costly and time-consuming novel drug development.
PMID: 33098146 [PubMed – as supplied by publisher]