Treating Fungal Keratitis with Oral Voriconazole Only: A Case Series.
Klin Monbl Augenheilkd. 2020 Dec 18;:
Authors: Chen D, Tan S, Zou W
BACKGROUND: To report the clinical effect of oral voriconazole only as a treatment for fungal keratitis.
HISTORY AND SIGNS: Three patients (1 female and 2 males) with culture-proven fungal keratitis (1 Mucoraceae, 1 Aspergillus, 1 Fusarium) were included in this study. The patients were treated with oral voriconazole 200 mg twice daily to observe the clinical response in the treatment of fungal keratitis.
THERAPY AND OUTCOME: The mean age of the patients was 51 years and the average treatment duration was 6 weeks. The corneal inflammation in these three patients was eliminated by oral voriconazole only.
CONCLUSIONS: This is the first reported case of oral voriconazole only as a treatment for fungal keratitis. We found that oral voriconazole has a significant clinical effect on the treatment of fungal keratitis.
PMID: 33339060 [PubMed – as supplied by publisher]