A case of influenza-associated invasive aspergillosis with cerebral hemorrhage due to infectious vasculopathy

Radiol Case Rep. 2021 Nov 26;17(2):326-331. doi: 10.1016/j.radcr.2021.10.031. eCollection 2022 Feb.


An invasive aspergillosis (IA) primarily occurs among immunocompromised patients. Recently with an influenzae infection prevalently spreading, influenzae-associated invasive aspergillosis (IAIA) has been reported occasionally. By contrast, neuroleptic malignant syndrome (NMS) occurs rarely in psychiatric patients who are treated with Olanzapine. We report a 43 years old male with psychiatric disorder who had developed IAIA followed by NMS and cerebral hemorrhage as the result of aspergillus invasion to cerebral vessels. He had also super-infection of COVID-19, 13 months later to be saved completely after invasive mechanical respiratory supports. From clinical aspects, we would emphasize that it is of importance to find earlier co-occurrence of IAIA patients with cerebral hemorrhage due to secondary infectious vasculopathy of IA.

PMID:34876959 | PMC:PMC8633528 | DOI:10.1016/j.radcr.2021.10.031

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