Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals

Open Forum Infect Dis. 2021 Dec 18;9(2):ofab638. doi: 10.1093/ofid/ofab638. eCollection 2022 Feb.


Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non-fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the “environmental” mutation TR34/L98H in the cyp51A gene.

PMID:35111868 | PMC:PMC8802793 | DOI:10.1093/ofid/ofab638

Source: Industry