Ochratoxin A: Occurrence and recent advances in detoxification
Toxicon. 2022 Feb 15:S0041-0101(22)00043-5. doi: 10.1016/j.toxicon.2022.02.010. Online ahead of print.
Ochratoxin A (OTA), one of the most important mycotoxins, is mainly produced by fungi in the genera Aspergillus and Penicillium, and commonly found in food and agricultural products. In addition to causing significant economic loss, the occurrence of OTA in foods poses a serious threat to human health. Therefore, it is very important to develop approaches to control or detoxify OTA contamination and thus ensure food safety. In this paper, we review the source and occurrence of OTA in food and agricultural products and the latest achievements in the removal and detoxification of OTA using physical, chemical, and biological methods, with specific attention to influencing factors and mechanisms related to the biodetoxification of OTA. Moreover, the advantages and disadvantages of these methods and their potential application prospect were also discussed.
PMID:35181402 | DOI:10.1016/j.toxicon.2022.02.010