A new sesquiterpenoid from the <em>aconitum</em>-derived fungus <em>Aspergillus fumigatus</em> M1

Nat Prod Res. 2022 May 24:1-9. doi: 10.1080/14786419.2022.2080207. Online ahead of print.


A new bergamotane sesquiterpenoid, fumigatanol (1), along with nine known compounds (210) were isolated from the Aconitum-derived fungus Aspergillus fumigatus M1. Their structures were established on the basis of extensive spectroscopic analyses, ECD experiment and NMR computational method. Antibacterial and cytotoxic activities of compound 1 were evaluated and no obvious antibacterial and cytotoxic activities were observed at concentrations of 256 μg/mL and 40.00 μM, respectively.

PMID:35609146 | DOI:10.1080/14786419.2022.2080207

Source: Industry