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Lateral Flow Device for detection of Aspergillus-specific Antigen


  • Aspergillus species

Product Code: OLM1906


20 Test Cassettes

Features and benefits

  • Aids in the diagnosis of Invasive Aspergillosis (IA)
  • Uses a monoclonal antibody that identifies antigenic mannoproteins generated by Aspergillus during active growth
  • Storage at room temperature
  • Culture-independent diagnostics
  • Detection from human serum and bronchoalveolar lavage fluid (BAL)
  • Results in 15-40 minutes
  • Simplified procedure with minimal specimen preparation
  • Flexible use: Non-haemorrhagic BAL fluid can be loaded directly onto the test pad
  • Enabling quick laboratory reporting to support clinical decision-making when time is of the essence

Test Principle

AspLFD uses a monoclonal antibody conjugated to nitrocellulose beads (NCB) to detect Aspergillus diagnostic antigen. The antibody-NCB conjugate binds specifically to Aspergillus diagnostic antigen in the patient sample to form a complex. The complex migrates along the strip until it is captured and concentrated on the test zone (T), where the same antibody has been bound. This causes a red line to appear on the strip.
If antigen concentrations are below detectable levels, no visible test line will be produced. Uncaptured NCB conjugate continues to flow towards the end of the strip where it is bound on the control (C) zone. Formation of a red C line indicates the test has been performed correctly.

Diagnostic specimens

  • Bronchoalveolar lavage (BAL) samples
  • Serum samples

Quality Assured

  • Validated on clinical samples
  • CE-IVD marked

Performance Characteristics

Highly sensitive and specific
Proven efficacy in the diagnosis of IA

Kit Contents

  • 20 Test Cassettes
  • Sample Pretreatment Buffer


Aspergillosis is an infection caused by Aspergillus, a common fungus that grows indoors and outdoors. Most people breathe in Aspergillus spores daily without becoming unwell. However, in persons whose immune systems have been compromised by cancer treatment, bone marrow transplantation, or other immune-related condition, aspergillosis can quickly become invasive pulmonary aspergillosis (IPA or IA). This is the most severe type of aspergillosis, and it happens when the infection spreads quickly from the lungs to the brain, heart, kidneys, or skin. The most common cause of IPA is A. fumigatus, followed by A. flavus and A. terreus. If left untreated, invasive aspergillosis can be lethal.

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